Impaired cough reflex in patients with recurrent pneumonia

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Impaired cough reflex in patients with recurrent pneumonia.

BACKGROUND A substantial proportion of patients with recurrent pneumonia do not have an apparent underlying condition, but they may have unknown defects in host defence mechanisms such as cough reflex. METHODS Capsaicin cough sensitivity was measured in seven patients with recurrent pneumonia but no underlying condition. Recurrent pneumonia was defined as at least two episodes of pneumonia in...

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Impaired urge-to-cough in elderly patients with aspiration pneumonia

BACKGROUND The down-regulation of the cough reflex in patients with aspiration pneumonia can involve both cortical facilitatory pathways for cough and medullary reflex pathways. In order to study the possible involvement of the supramedullary system in the down-regulation of cough reflex, we evaluated the urge-to-cough in patients with aspiration pneumonia. METHODS Cough reflex sensitivity an...

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Sensitivity of the cough reflex in patients with chronic cough.

Cough may occur in association with excess bronchial secretions and may, therefore, be productive. However, in a proportion of patients the cough is non-productive and a possible association with an enhanced response of the cough reflex has been postulated. Using the irritant capsaicin, the sensitivity of the cough reflex was measured in 363 individuals. A questionnaire was used to divide subje...

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Impaired efficacy of cough in patients with Parkinson disease.

STUDY OBJECTIVES Aspiration pneumonia, a leading cause of death in patients with Parkinson disease (PD), usually occurs at the advanced stages of the disease. We investigated both motor and sensory components of cough and induced-sputum substance P (SP) concentrations in patients with early and advanced stages of PD to assess whether cough efficacy is impaired in PD. SUBJECTS Fifteen female p...

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Presence of Chapman reflex points in hospitalized patients with pneumonia.

The authors undertook a case control study to determine whether hospitalized patients with pneumonia had reflex points in the anterior chest wall as described by Frank Chapman, DO, specifically those classified as relating to the lung. Sixty-nine hospitalized patients were enrolled in the study. Patients with an admitting diagnosis of pneumonia were compared to those without pneumonia as their ...

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ژورنال

عنوان ژورنال: Thorax

سال: 2003

ISSN: 0040-6376

DOI: 10.1136/thorax.58.7.645-b